山东农业大学生命科学校聘教授张毅导师

姓名：张毅  学历：博士研究生  所属部门：生命科学学院植物生理系  职称：校聘教授

招生专业：植物生理            邮箱: yizhang@sdau.edu.cn

个人简介：

张毅，博士，校聘教授，硕士生导师，山东省“泰山学者”青年专家。2010年在山东师范大学获得理学学士学位，2017年获中国科学院大学理学博士学位。2019-2021年在丹麦哥本哈根大学进行博士后研究。2022年9月进入山东农业大学生命科学学院小麦育种全国重点实验室工作。近年来主持国家自然科学基金青年项目、山东省自然科学基金博士项目，在Nature communications、Nature Food、Genome Biology、Plant Journal等学术刊物上发表多篇研究论文。

个人荣誉：中国科学院大学优秀毕业生

教学工作：植物生理学、植物生理学实验

研究方向：

1. 利用基因编辑技术对小麦进行遗传改良。

2. 利用基因编辑工具对作物光合作用相关基因进行改造，提高作物的光合效率。

主持科研项目：

1. 国家自然科学基金青年项目，31800304，结题。

2. 山东省自然科学基金项目博士项目，ZR2018BC016，结题

3. 山东省泰山学者青年专家项目，在研。

发表论文:

1. Li Z¹, Zhong F¹, Guo J, Chen Z, Song J*, Zhang Y*. (2022). Improving wheat salt tolerance for saline agriculture. Journal of Agricultural and Food Chemistry, 70 (48), 14989-15006.

2. Zhang Y, Pribil M, Palmgren M*, Gao C*. (2020). A CRISPR way for accelerating improvement of food crops. Nature Food, 1, 200-205.

3. Zhang Y, Palmgren M*. (2020). Gene-editing in plants no longer requires tissue culture. Frontiers of Agricultural Science & Engineering, 7, 229-230.

4. Zhang Y, Massel K, Godwin I D, Gao C*. (2018). Applications and potential of genome editing in crop improvement. Genome Biology, 19, 210.

5. Zhang Y¹, Li D¹, Zhang D, Zhao X, Cao X, Dong L, Liu J, Chen K, Zhang H, Gao C*, Wang D*. (2018). Analysis of the functions of TaGW2 homoeologs in wheat grain weight and protein content traits. Plant Journal, 94, 857-866.

6. Zhang Y, Gao C*.(2017).Recent advances in DNA-free editing and precise base editing in plants. Emerging Topics in Life Sciences, 1, 161-168.

7. Zhang Y¹, Liang Z¹, Zong Y¹, Wang Y, Liu J, Chen K, Qiu J, Gao C*.(2016). Efficient and transgene-free genome editing in wheat through transient expression of CRISPR/Cas9 DNA or RNA.Nature Communications, 7, 12617.

8. Zhang Y, Li J, Gao C*. (2016). Generation of stable transgenic rice (Oryza sativa L.) by Agrobacterium-mediated transformation. Current Protocols in Plant Biology,1, 235-246.

9. Ji X¹, Si X¹, Zhang Y, Zhang H, Zhang F, Gao C*. (2018) Conferring DNA virus resistance with high specificity in plants using virus-inducible genome-editing system. Genome Biology, 19, 197.

10. Liang Z, Chen K, Yan Y, Zhang Y, Gao C*. (2018). Genotyping genome-edited mutations in plants using CRISPR ribonucleoprotein complexes. Plant Biotechnology Journal, 16, 2053-2062.

11. Liang Z¹, Chen K¹, Zhang Y, Liu J, Yin K, Qiu J, Gao C^*. (2018). Genome editing of bread wheat using biolistic delivery of CRISPR/Cas9 in vitro transcripts or ribonucleoproteins. Nature Protocols, 13, 413-430.

12. Meng X¹, Yu H¹, Zhang Y, Zhuang F, Song X, Gao S, Gao C*, Li J*. (2017). Construction of a genome-wide mutant library in rice using CRISPR/Cas9. Molecular Plant, 10, 1238-1241.

13. Liang Z¹, Chen K¹, Li T, Zhang Y, Wang Y, Zhao Q, Liu J, Zhang H, Liu C, Ran Y, Gao C^*. (2017). Efficient DNA-free genome editing of bread wheat using CRISPR/Cas9 ribonucleoprotein complexes. Nature Communications, 8, 14261.

14. Shan Q, Zhang Y, Chen K, Zhang K, Gao C*. (2015). Creation of fragrant rice by targeted knockout of the OsBADH2 gene using TALEN technology. Plant Biotechnology Journal, 13, 791-800.

15. Ji X¹, Zhang H¹, Zhang Y, Wang Y, Gao C*.(2015). Establishing a CRISPR-Cas-like immue system conferring DNA virus resistance in plants. Nature Plants, 1, 15144.

16. Zhang K¹, Liu J¹, Zhang Y, Yang Z, Gao, C*. (2015). Biolistic genetic transformation of a wide range of Chinese elite wheat (Triticum aestivum L.) varieties. Journal of Genetics and Genomics, 42, 39-42.

17. Wang S, Li S, Liu Q, Wu K, Zhang J, Wang S, Wang Y, Chen X, Zhang Y, Gao C, Wang F, Huang H, Fu X*. (2015). The OsSPL16-GW7 regulatory module determines grain shape and simultaneously improves rice yield and grain quality. Nature Genetics, doi:10.1038/ng.3352.

18. Wang Y¹, Cheng X¹, Shan Q, Zhang Y, Liu J, Gao C*, Qiu J*. (2014) Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew. Nature Biotechnology, 32, 947-951.

19. Shan Q¹, Wang Y¹, Li J¹, Zhang Y, Chen K, Liang Z, Zhang K, Liu J, Qiu J*, Gao C*. (2013). Targeted genome modification of crop plants using a CRISPR-Cas system. Nature Biotechnology, 31, 686-688.

20. Shan Q¹, Wang Y¹, Chen K¹, Liang Z, Li J, Zhang Y, Zhang K, Liu J, Voytas D F, Zheng X, Zhang Y*, Gao C*. (2013). Rapid and efficient gene modification in rice and Brachypodium using TALENs. Molecular Plant, 6, 1365-1368.

授权专利：

1. 一种提高小麦产量的方法，专利号：CN106978436B, 发明人：高彩霞，张毅（已授权）。

2. A method for site-directed modification of whole plant through gene transient expression. Patent number: PCT/CN2016/072352. Patent inventor: Caixia Gao, Yi Zhang, Zhongyi Wu, Kang Zhang (published in many counties and granted in Australia and Eurasian Patent Organization).